I listened to the first disc of On Air - Live at the BBC, Volume 2 this morning and noticed something about "Lend Me Your Comb" (and in referencing the liner notes, I discovered that this is the same recording as that on Anthology 1). The lines "Unless we come in / The way we went out" have opposite melodic arcs to portray those opposite directions. "Unless we come in" generally ascends (G# A G# A B), and "The way we went out" generally descends (G# A G# F# E).
I also noticed that "home" in the line "We gotta go home" is sung to the tonic note (E), musically giving a sense of "home."
These features are also present in Carl Perkins' version, which - according to the liner notes - is what the Beatles based their version on.